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. 2020 Aug 13;9:F1000 Faculty Rev-982. [Version 1] doi: 10.12688/f1000research.20419.1

Table 5. Potential chronic sequelae of Stevens–Johnson syndrome – toxic epidermal necrolysis.

Organ system Sequelae
Skin Dyspigmentation, eruptive nevi, milia, nail dystrophy, alopecia, scarring, and heterotopic ossification
Ocular Sicca symptoms, trichiasis, corneal vascularization, corneal scarring, symblepharon, keratitis, and blindness
Oral Xerostomia, synechiae, chronic gingivitis, dental caries, periodontal disease, taste abnormalities, abnormal
dental development, and candidiasis
Gastrointestinal Pancreatitis, colon necrosis, esophageal stenosis and webs, microstomia, and persistent intestinal ulcers
Genitourinary Vaginal stenosis, labial fusion, hydrocolpos, hematocolpos, dyspareunia, vaginal dryness, and urethral stenosis
Pulmonary Chronic obstructive bronchitis and bronchiolitis, bronchiectasis, and pharyngeal and laryngeal scarring
Autoimmune Sjögren syndrome, systemic lupus erythematosus, and autoimmune thyroiditis
Psychiatric Anxiety and depression

Adapted with permission from Peter et al., 19.