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. 2020 Aug 17;3(8):e2011620. doi: 10.1001/jamanetworkopen.2020.11620

Table 2. Association of Urinary BPA Levels With All-Cause Mortality and With Cause-Specific Mortality.

Variable Tertile of urinary BPA level, hazard ratio (95% CI)
1 2 3
Median BPA level, ng/mL 0.7 2.1 5.7
All-cause mortality
Deaths per person-years 133 per 11897 100 per 12268 111 per 12349
Model 1a 1 [Reference] 1.06 (0.76-1.47) 1.51 (1.07-2.13)
Model 2b 1 [Reference] 1.10 (0.78-1.55) 1.49 (1.01-2.19)
CVD mortality
Deaths per person-years 32 per 11897 18 per 12268 21 per 12349
Model 1a 1 [Reference] 1.13 (0.54-2.37) 1.68 (0.82-3.44)
Model 2b 1 [Reference] 1.10 (0.53-2.31) 1.46 (0.67-3.15)
Cancer mortality
Deaths per person-years 31 per 11897 22 per 12268 22 per 12249
Model 1a 1 [Reference] 1.13 (0.45-2.81) 1.05 (0.44-2.47)
Model 2b 1 [Reference] 1.12 (0.48-2.63) 0.98 (0.40-2.39)

Abbreviations: BPA, bisphenol A; CVD, cardiovascular disease.

a

Adjusted for age, sex, race/ethnicity, and urinary creatinine levels.

b

Model 1 plus adjusted for educational level, family income status, smoking, alcohol drinking, physical activity, total energy intake, Healthy Eating Index 2010 score, and body mass index.