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Interaction between IL-1β and I-kB kinase/NF-kB signalling pathway, which have positive activation of Nuclear Factor Kappa B Subunit 1. NF-kB is a pleiotropic transcription factor present in almost all cell types. It is the endpoint of a series of signal transduction events initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Positive activation of CASP8 (score: 0.900).
