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The deletion of IDO2 affects the mRNA expression of key cytokines involved in the pathogenesis of psoriasis. Quantitative real-time PCR analysis of the ear before and 24 h, 48 h, and 7 days after IMQ treatment. Data are presented as mean ± SEM. * p < 0.05, ** p < 0.01 (Student’s t-test). n = 4–7. WT: wild type, IDO: indoleamine 2,3-dioxygenase, IMQ: imiquimod, KO: knockout.
