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. 2020 Jul 28;21(15):5352. doi: 10.3390/ijms21155352

Figure 1.

Figure 1

Behavioral results from the retrieval test in a neutral context (mean and SEM) are shown in Panel (A). Panels (B–H) show zif268 expression reported as a percentage (mean and SEM) of total DAPI present in the same section. Zif268 was increased in both 15-month-old and 22-month-old animals relative to 3-month-old animals in the medial prefrontal cortex (mPFC) (B), the aRSC (C), pRSC (D), dorsal hippocampus (DH) (E), ventral hippocampus (VH) (F), LA (G), and ventrolateral periaqueductal gray (vlPAG) (H). In the pRSC, VH, LA, and vlPAG, 22-month-old animals also showed increased zif268 relative to 15-month-old animals. Asterisks indicate p < 0.05; pound signs indicate p < 0.10. White dots represent individual rats.