Figure 4.
Animals were divided into two groups (high freezers and low freezers) based on a median split of performance in the Post-CS (conditional stimulus) period during the retrieval test. Results from the Post-CS period during the retrieval test (mean and SEM) are shown in Panel (A), where impaired animals froze less than unimpaired animals. Panels (B–H) show zif268 expression reported as a percentage (mean and SEM) of total DAPI present in the same section. Impaired animals had increased zif268 relative to unimpaired in the mPFC (B). While there was a trend in the aRSC (C), impaired animals showed increased zif268 in the pRSC (D). No differences were seen in the DH (E), but impaired animals had increased zif268 relative to unimpaired animals in the VH (F). This finding held in the LA (G) and the vlPAG (H). Asterisks indicate p < 0.05; pound signs indicate p < 0.10. White dots represent individual rats.
