Table 2.
The comparison of the 3D lung co-culture model presented in this study to commercially available 3D lung co-culture models consisting of primary cells.
| Property | The Presented Model in This Study | Commercially Available Models Consisting of Primary Cells [30,48] |
|---|---|---|
| Ease of assembling the model | Easy | Sold as ready-to-use |
| Adjusting/ tuning based on desired investigation endpoints | Possible | Not possible |
| Inclusion of immune cells | Yes | No * |
| Possibility to use classical cell culture media | Yes | No |
| Overall cost | Low | High |
| Suitability to be used for long-term experiments | No | Yes |
| Barrier tightness (trans-epithelial electrical resistance) | Low | High |
* Can be included by the end-user, but requires an extensive optimization step as immune cells are cultured in a different and complex cell media as opposed to commercially available models.