(a)
| Controls | Cases | p-Value | ||
|---|---|---|---|---|
| Gender (Male/Female) | 1066/715 | 1027/727 | 0.43 | |
| Age (Mean ± SD) | 68.72 ± 10.18 | 68.25 ± 10.42 | 0.32 | |
| First Degree Relatives With CRC | n (available) | 1781 | 1754 | 0.009 |
| Yes (%) | 11.3 | 14.3 | ||
| No (%) | 88.7 | 85.8 | ||
| Education | n (available) | 1781 | 1754 | <0.0001 |
| Low (%) | 53.3 | 62.9 | ||
| Medium (%) | 25.3 | 20.5 | ||
| High (%) | 21.4 | 16.6 | ||
| Red meat Consumption | n (available) | 1781 | 1754 | <0.0001 |
| Low (%) | 10.7 | 8.2 | ||
| Medium (%) | 85.1 | 84.7 | ||
| High (%) | 4.2 | 7.1 | ||
| Alcohol Consumption (g/day) | n (available) | 1781 | 1754 | 0.012 |
| no intake | 14.7 | 16.3 | ||
| 0.1–5.7 | 23.4 | 21.0 | ||
| 5.7–13.3 | 21.1 | 20.8 | ||
| 13.3–28.6 | 23.6 | 21.1 | ||
| ≥28.6 | 17.2 | 20.9 | ||
| Regular Smoking | n (available) | 1781 | 1754 | 0.011 |
| Never (%) | 52.2 | 47.9 | ||
| Current (%) | 47.8 | 52.1 | ||
| Diabetes | n (available) | 1781 | 1754 | 0.0003 |
| Yes (%) | 13.7 | 18.2 | ||
| No (%) | 86.4 | 81.8 | ||
| BMI (kg/m2) | n (available) | 1781 | 1754 | <0.0001 |
| <18.5 (%) | 0.7 | 0.97 | ||
| 18.5–25 (%) | 37.1 | 31.07 | ||
| 25–30 (%) | 47.0 | 47.32 | ||
| >30 (%) | 15.2 | 20.64 | ||
| NSAID Use | n (available) | 1781 | 1754 | <0.0001 |
| No (%) | 63.1 | 74.0 | ||
| Yes (%) | 37.0 | 26.0 | ||
| Ever Colonoscopy | n (available) | 1781 | 1754 | <0.0001 |
| No (%) | 46.9 | 79.2 | ||
| Yes (%) | 53.1 | 20.8 |