(b)
| Overall Survival | Recurrence-Free Survival | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | SNP | Location | Alleles | Alive | Deceased | HR 1 (95%-CI) | p | q | Alive | Deceased | HR 1 (95%-CI) | p | q |
| KDR | rs2305948 | V297I | CC | 934 | 424 | [1] | 944 | 414 | [1] | ||||
| CT | 209 | 113 | 1.27 (1.06–1.53) | 0.01 | NA | 225 | 97 | 1.14 (0.92–1.41) | 0.23 | NA | |||
| TT | 12 | 9 | 11 | 10 | |||||||||
| CT/TT | 221 | 122 | 1.28 (1.04–1.57) | 0.02 | NA | 236 | 107 | 1.09 (0.86–1.37) | 0.47 | NA | |||
1 Hazard ratios for log-additive and dominant models, adjusted for age, sex, stage, grade, BMI, alcohol consumption. Abbreviations: SNP: single nucleotide polymorphism; HR: hazard ration; CI: confidence interval; NA: not applicable.