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. 2020 Aug 11;11:757. doi: 10.3389/fpsyt.2020.00757

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Copyright © 2020 Chen, Shi, Liu, Wang, Chen, Tang, Yan, Yao and Lu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Volcano map of differentially expressed miRNAs. The horizontal axis is the logarithm of the fold change value based on 2, and the vertical axis is the negative logarithm of the p value based on 10. Blue dots represent down-regulated miRNAs with statistically significant differences in patients comparing healthy subjects. Red dots represent miRNAs that are up-regulated in patients, and grey dots represent miRNAs that have no significant differences in expression values between the patients and healthy controls. (B) Heat map of differentially expressed miRNAs. The abscissa represents the subject names between groups, and the ordinate represents the differentially expressed miRNAs. Differentiated miRNAs are expressed in red with high expression values and those with low expression values are in green.