Figure 5.

Volume density of synaptic vesicles in the active zones of neuromuscular synapses of mice inoculated with sera from amyotrophic lateral sclerosis (ALS) patients. All sera from ALS patients induced a significant increase in the number of active zone synaptic vesicles. Data are represented as the mean value ± standard error of the mean (s.e.m.). Statistical evaluation was determined using a one-way analysis of the variance (ANOVA) with the least significant difference post-hoc pairwise comparison. *: p < 0.05; **: p < 0.01; ***: p < 0.001.