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. 2020 Aug 11;14:839. doi: 10.3389/fnins.2020.00839

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Copyright © 2020 Seki.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A new hypothetical model of the real state of human adult hippocampal neurogenesis. (A) Changes in the levels of neuronal production, immature neuronal marker-positive (INM+) newly generated neurons, and INM+ neurons in the adult human SGZ during aging. (B) The origin of INM+ neurons in the adult human hippocampus. NP, proliferating neural progenitor cells.