FIGURE 6.

MBTD1 is required for induction of key decidual marker genes in decidualizing primary HESCs. (A) Transcript levels of MBTD1, IGFBP1, and PGR in HESCs transfected with control or MBTD1 siRNAs and induced to decidualize for 3 days. (B) WNT4, FOXO1A, and GREB1 expression in HESCs transfected with control or MBTD1 siRNAs and induced to decidualize for 3 days. Representative data from three replicates from one patient sample are shown as mean ± SEM. The experiment repeated three times, n = 3; *P < 0.05, **P < 0.01, ***P < 0.001, ns, non-significant.