Hepatic levels of the PR domain containing 16 (PRDM16), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), Mitofusin-2 (MFN-2), and Dynamin-like 120 kDa protein (OPA-1) in lean, HFD-, and HFD + PSO-treated mice. (A) Representative western blots for PRDM16, PGC-1α, and β-actin. (B) Quantitation of the hepatic levels of PRDM16. (C) Quantitation of the hepatic levels of PGC-1α. (D) Representative western blots for MFN-2, OPA-1, and β-actin. (E) Quantitation of the hepatic levels of MFN-2. (F) Quantitation of the hepatic levels of OPA-1. * = different p < 0.05 from corresponding value in lean mice. # = different p < 0.05 from corresponding value in HFD mice. n = 6/group.