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Schematic depiction of PSO effects on fatty liver. PSO attenuates obesity-induced hepatic steatosis and fibrosis through an increase in the antioxidant gene HO-1 and the mitochondrial signaling pathways PRDM 16, PGC1α, MFN-2, and OPA1. Additionally, there is a decrease in the fibrotic markers MMP2, MMP9 and inflammatory adipokines NF-κB, Nov/CCN3, and IL-6, resulting in a healthy liver.
