HTS	High-throughput screening
VDR	Vitamin D receptor: NR1I1
AF-1	Activation function 1
Zn	Zinc
DBD	DNA-binding domain
NLS	Nuclear localization signal
LBD	Ligand-binding domain
AF-2	Activation function 2
ER	Estrogen receptor, ERα: NR3A1, ERβ: NR3A2
AR	Androgen receptor: NR3C4
RXR	Retinoid X receptor, RXRα: NR2B1, RXRβ: NR2B2, RXRγ: NR2B3
PPIs	Protein–protein interactions
HSP	Heat shock protein
NMR	Nuclear magnetic resonance
SPR	Surface plasmon resonance
LOPAC	Library of Pharmacologically Active Compounds
PPAR	Peroxisome proliferator activated receptor, PPARα: NR1C1, PPARβ/δ: NR1C2, and PPARγ: NR1C3
T2D	Type 2 diabetes
PSCs	Pluripotent stem cells
Em	Embryonic
ExEm	Extraembryonic
LNCaP	Lymph Node Carcinoma of the prostate
TNF	Tumor Necrosis Factor
NF	Nuclear factor
GFP	Green fluorescence protein
NIH	National Institutes of Health
FXR	Farnesoid X receptor, FXR: NR1H4, FXRβ: NR1H5
FRET	Fluorescence resonance energy transfer
FDA	Food and Drug Administration
SBDD	Structure-based drug discovery
NCATS	National Center for Advancing Translational Sciences
NCGC	NCATS Chemical Genomics Center (NCGC)
ELF	European Lead Factory
SMEs	Small and medium enterprises
CNCL	Chinese National Compound Library
DDI	Drug Discovery Initiative
BINDS	Basis for Supporting Innovative Drug Discovery and Life Science Research
CAR	Constitutive androstane receptor: NR1I3
GR	Glucocorticoid receptor: NR3C1
LXR	Liver X receptor, LXRα: NR1H3, LXRβ: NR1H2
PR	Progesterone receptor: NR3C3
PXR	Pregnane X receptor: NR1I2
RAR	Retinoic acid receptor, RARα: NP1B1, RARβ: NP1B2, RARγ: NR1B3
TR	Thyroid hormone receptor, TRα: NP1A1, TRβ: NP1A2