Figure 1.

Expression of small heat shock proteins (sHsps) in the eye lens and other tissues. (A) Examples of differences in the expression of sHsps (at abundant levels) are shown for a selection of three tissues (eye lens, brain, muscle) [25,54,55]. (B) Simplified schematic model of the eye lens, epithelial cells, lens fiber cells (organelle free cells in light blue) and primary fiber cells [56]. Total protein concentration increases within the lens eyes. αA- and αB-crystallin concentration increase or decrease, respectively, during differentiation of bovine lens cells [57].