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EVI1 downregulates miR-449a in NPC cells. (A) Expression of miR-449a in C666-1 cells transfected with EVI1 siRNA or pEFzeo-EVI1 plasmid. (B) Expression levels of miR-449a in ICG-001-treated EBV-positive (C666-1 and C17) and EBV–negative (Hone-1) NPC cells. (C) Effect of miR-96 on the expression of miR-449a in C666-1 cells. At least three individual experiments were performed. * p < 0.05, ** p < 0.01 compared with the corresponding control.
