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Hypothetical mode of anti-tumor action of ICG-001 in NPC. (A) Involvement of miR-150/CD44 axis in the migration of NPC cells (23). (B) Regulation of NPC tumor spheres growth via miR-145/SOX2 axis (22). (C) Regulation of NPC cell migration and growth of tumor spheres via miR-96/Evi1/miR-449s axis. ⇑: Upregulated expression in ICG-001-treated NPC cells.
