Table 4.

UPF3A-induced protein regulation (>1.5 fold in at least two biological replicates).

Protein Name	Gene Name	Ratio pUPF3A/dUPF3A
GTPase-activating protein and VPS9 domain-containing protein 1	GAPVD1	2.19
DNA (cytosine-5)-methyltransferase 1	DNMT1	1.88
Tumor protein D52	TPD52	1.70
COP9 signalosome complex subunit 3	COPS3	1.65
U1 small nuclear ribonucleoprotein 70 kDa	SNRNP70	1.64
DNA replication licensing factor MCM7	MCM7	1.49
Nucleolar protein 56	NOP56	−1.51
Phosphoglucomutase-1	PGM1	−1.51
Superoxide dismutase [Cu-Zn]	SOD1	−1.53
NAD(P)H dehydrogenase [quinone] 1	NQO1	−1.56
Microsomal glutathione S-transferase 1	MGST1	−1.56
Core histone macro-H2A.1	H2AFY	−1.60
UDP-glucose 6-dehydrogenase	UGDH	−1.61
Sulfide:quinone oxidoreductase. mitochondrial	SQRDL	−1.67
Glutathione S-transferase P	GSTP1	−1.67
Hydroxymethylglutaryl-CoA synthase. cytoplasmic	HMGCS1	−1.71
Mevalonate kinase	MVK	−1.74
NADP-dependent malic enzyme	ME1	−1.75
Solute carrier family 2. facilitated glucose transporter member 1	SLC2A1	−1.80
Ubiquitin-40S ribosomal protein S27a	RPS27A	−1.80
Catalase	CAT	−1.80
Microsomal glutathione S-transferase 3	MGST3	−1.80
Diphosphomevalonate decarboxylase	MVD	−1.87
Lanosterol synthase	LSS	−1.88
Gamma-glutamylcyclotransferase	GGCT	−1.90
7-dehydrocholesterol reductase	DHCR7	−1.96
Long-chain-fatty-acid--CoA ligase 1	ACSL1	−1.97
Histone H2A.V	H2AFV	−2.00
Zinc transporter 1	SLC30A1	−2.03
Prostaglandin reductase 1	PTGR1	−2.11
Squalene synthase	FDFT1	−2.52
Aldo-keto reductase family 1 member C1;	AKR1C1	−2.90
Sequestosome-1	SQSTM1	−3.37
Junction plakoglobin	JUP	−4.41
Metallothionein-2	MT2A	−5.88

* Mean of ratios from three biological replicates.