Table 5.
Top 10 up-regulated and top 10 down-regulated phosphopeptides upon UPF3Aexpression.
| Protein Name | Gene Name | Phosphosite | Ratio pUPF3A/dUPF3A |
|---|---|---|---|
| Lamin-B1 * | LMNB1 | T20, S23 | 2.39 |
| Nucleophosmin | NPM1 | S254 | 2.35 |
| Catenin delta-1 § | CTNND1 | S349 | 2.15 |
| Cell division cycle 5-like protein | CDC5L | S303 | 2.05 |
| Multifunctional protein ADE2; Phosphoribosylaminoimidazole-succinocarboxamide synthase | PAICS | S27 | 2.01 |
| Neuroblast differentiation-associated protein AHNAK | AHNAK | S5763 | 1.96 |
| General transcription factor IIF subunit 1 | GTF2F1 | S224 | 1.95 |
| Importin subunit alpha-3 | KPNA4 | S60 | 1.88 |
| MARCKS-related protein | MARCKSL1 | S104 | 1.84 |
| Sister chromatid cohesion protein PDS5 homolog A | PDS5A | S1206 | 1.77 |
| Serine/arginine repetitive matrix protein 2 | SRRM2 | S377 | −2.27 |
| Tumor protein D52 | TPD52 | S223 | −2.30 |
| Tumor protein D54 | TPD52L2 | S19 | −2.71 |
| Serine/arginine repetitive matrix protein 2 * | SRRM2 | S876 | −2.90 |
| RNA-binding protein 14 | RBM14 | S618 | −3.20 |
| Serine/arginine-rich splicing factor 9 | SRSF9 | S211, S216 | −3.41 |
| Nuclear mitotic apparatus protein 1 | NUMA1 | S1969 | −3.43 |
| Catenin delta-1 | CTNND1 | S230 | −3.58 |
| Catenin delta-1 § | CTNND1 | S346, S349, S352 | −3.74 |
| Ras-related protein Rab-7a | RAB7A | S72 | −5.34 |
* Mean of ratios from three biological replicates; § Phosphosite (S349) identified on both mono and multiple phosphorylated peptides with different expression levels.