Figure 1.

ACE2 and general immune dysregulation analysis in tobacco and electronic cigarette (e-cig) users. (A) Boxplots of ACE2 expression in current and former smokers, including those that have quit for less than and more than 15 years. (B) Boxplots of ACE2 expression in control and e-cigarette users, including patients who have never smoked tobacco and those who are former tobacco smokers. (C) Radar plots comparing immune cell infiltration across smokers, e-cigarette users vaping nicotine-less, flavor-less e-cigs, and vapers who used e-cigs containing nicotine and flavors. Greater immune cell infiltration is indicated by a value closer to zero and farther away from the center of the radar plot.