Table 2.
Significantly dysregulated inflammasome-related gene expression.
| Gene | Geo2R | Kruskal-Wallis | Cohort | ||
|---|---|---|---|---|---|
| p-Value | logFC | p-Value | logFC | ||
| CCL5 | 0.85415 | 0.024121 | 0.273192 | 0.009959 | E-cig vs. None |
| 0.049094 | 0.463617 | 0.032858 | 0.0421 | E-cig vs. Former Smokers | |
| 0.897886 | 0.077011 | Current vs. Former Tobacco Smokers | |||
| CXCL1 | 0.622626 | 0.083064 | 0.241121 | 0.016747 | E-cig vs. None |
| 0.274418 | 0.177215 | 0.395149 | 0.00718 | E-cig vs. Former Smokers | |
| 0.008846 | 1.553637 | Current vs. Former Tobacco Smokers | |||
| CXCL2 | 0.802924 | −0.03393 | 0.429555 | 0.004948 | E-cig vs. None |
| 0.359789 | 0.122607 | 0.413227 | 0.003556 | E-cig vs. Former Smokers | |
| 0.008202 | 2.113189 | Current vs. Former Tobacco Smokers | |||
| NLRP3 | 0.995982 | 0.000195 | 0.918813 | 0.002349 | E-cig vs. None |
| 0.183356 | 0.07004 | 0.056236 | 0.013534 | E-cig vs. Former Smokers | |
| 0.758085 | 0.158417 | Current vs. Former Tobacco Smokers | |||
| NOD2 | 0.317884 | 0.034773 | 0.459914 | 0.001984 | E-cig vs. None |
| 0.207633 | 0.099462 | 0.041595 | 0.014107 | E-cig vs. Former Smokers | |
| 0.777691 | 0.16816 | Current vs. Former Tobacco Smokers | |||
| PYCARD | 0.659102 | −0.0204 | 0.721277 | −0.00158 | E-cig vs. None |
| 0.048781 | 0.187701 | 0.065034 | 0.017268 | E-cig vs. Former Smokers | |
| 0.100456 | 0.272032 | Current vs. Former Tobacco Smokers | |||