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Pro- and anti-inflammatory changes of the immune system during the course of sepsis and septic shock. HLA-DR, human leukocyte antigen-D related; IgM/G, immunoglobulin M/G; IL, interleukin; IFN-γ, Interferon gamma; PAMPs, pathogen-associated molecular patterns; TNF-α, tumor necrosis factor alpha; TLR, toll-like receptor.
