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The central role of intravenous immunoglobulins IgGAM on the innate and adaptive immune response, using different regulatory pathways to interact with the cellular and humoral components. IFN, interferon; Ig, immunoglobulin; IgGAM, immunoglobulin G/A/M; IL, interleukin; NK cell, natural killer cell; Teff cell, effector T cell; TH cell, helper T cell; Treg cell, regulatory T cell.
