. 2020 Aug 11;11:1765. doi: 10.3389/fimmu.2020.01765

Table 2.

Biological features of patients with CD3⁻CD4⁺ T-cell associated hypereosinophilia.

Pat	Routine biology					Max HE	T cell investigations in blood
	Lympho G/L	Eosino G/L	IgE KU/L	IgG g/L	IgM g/L	G/L	CD3⁻CD4⁺ % lympho	CD3⁻CD4⁺ G/L	TCR rearr^b (β and/or γ)
P01	1.47	3.76	1061	15.5	72	12.35	43	0.63	+
P02	4.67	5.54	340	7	3.1	17.10	71	3.00	+^c
P03	2.86	11.61	10360	22.26	22.6	11.61	60	1.72	+
P04	2.24	2.97	478	19.2	2.36	5.50	10	0.22	–
P05	2.12^a	19.28^a	15^a	12.7	7.74^a	19.28	30^a	1.73^a	+^{a, c}
P06	1.37	0.77	7849	10.3	1.23	0.77	8.4	0.12	+
P07	1.98	0.71	13	9.48	1.87	9.60	0.5	0.01	–
P08	1.78	7.35	2896	14.8	1.66	13.80	1.9	0.03	(+)
P09	1.97	4.47	45^a	14	1.24	5.00	7	0.14	(+)
P10	1.70	2.14	838^a	55.3^a	11.5^a	15.00	2	0.03	–
P11	1.43	2.00	57^a	17.2	6.39	4.20	0.72	0.01	(+)
P12	2.43	6.09	225	16.7	2.24	14.04	23	0.56	+
P13	1.70	2.40	>5000	11.9	0.78	4.16	29^a	1.15^a	+^a
P14	2.00	3.48	79^a	17.4	1.18	4.10	71	1.42	+
P15	2.22	2.40	15	14.9	0.86	6.20	1.18	0.03	–
P16	0.78	0.60	326	13.4	1.12	1.56	7.37	0.06	+
P17	3.13	3.00	>5000	33.6	1.11	5.50	0.46	0.01	–
P18	1.24	1.17	66^a	13	0.97	4.60	13	0.16	(+)^{a, c}
P19	1.94	5.84	19	11.3	1.31	7.29	0.15^a	0.002^a	–^a
P20	2.45	6.36	<2	14.3	2.17	22.40	2.7	0.07	+
P21	1.56	0.90	12	18.2	1.38	0.90	22	0.34	+
P22	3.86	11.15	869	12.5	0.9	11.15	0.7	0.03	–
P23	3.54	53.03	nd	7.6	10.76	53.03	0.86^a	0.03^a	–^a
P24	3.17	4.20	22	12.2	2.42	40.00	0.46	0.02	–
P25	4.77	3.87	461	14.7	3.4	6.27	57	2.71	+
P26	2.97	10.60	231	10.5	1.27	12.40	1	0.03	–^c

Maintenance treatment ongoing at time assessment was performed.

Results for TCR gene rearrangement patterns are recorded as follows: + clonal pattern, (+) clonal peak on a polyclonal background, - polyclonal.

Not assessed at time of discovery of CD3⁻CD4⁺ T cells; result shown is the first assessment thereafter.

Normal values: lymphocytes 1.340–3.950 G/L; eosinophils 0.1–0.5 G/L; IgE < 120 KU/L; IgG 6–15 g/L; IgM 0.4–2.5 g/L.

HE, hypereosinophilia, nd, not done, Tx, treatment, rear, rearrangement.