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Effect of tomatine on melanoma cancer cell invasion. (a) Tomatine-dependent decrease of cancer cells invasion through matrigel-coated porous filters (magnification 50×). (b) Percentage of invasion in melanoma cells treated with tomatine (0.5–1 µM in terms of α-tomatine). Data are shown as mean ± SD of three different experiments performed in triplicate. ** p < 0.01 and *** p < 0.001, relative to vehicle-treated cells.
