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. 2020 Aug 18;18:319. doi: 10.1186/s12967-020-02480-z

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Intersection between the coronavirus-host interactome and cellular targets of drugs inhibiting coronavirus replication. Viral proteins are in red, host proteins in blue and small molecules in cyan. Virus-host PPIs are from the coronavirus-host interactome. Compound-target interactions were retrieved from the Drug Repurposing Hub database. For each molecule, stars indicate how many screenings out of the four compiled for this analysis identified their anti-coronavirus activity