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. 2020 Jul 25;21(15):5291. doi: 10.3390/ijms21155291

Table 3.

Features of some of the most commonly used imaging radionuclides.

Modality Radio-nuclide Physical Half-Life Production Target /Parent Isotope Primary Precursor Main Emissions
SPECT 99mTc 6.01 h Generator
(99Mo/99mTc)
99Mo, parent isotope [99mTc]TcO4Na γ, 141 keV
111In 2. 81 d Cyclotron
111Cd(p,n)111In
112Cd(p,2n)111In
111/112Cd-enriched sample [111In]InCl γ, 245, 171 keV
67Ga 78.3 h Cyclotron
(68Zn(p, 2n)67Ga)
68Zn-enriched sample [67Ga]GaCl3 γ, 300, 181, 93 keV
123I 13.2 h Cyclotron
(124Te(p, 2n)123I)
124Te-enriched sample [123I]I2 γ, 159 keV
PET 13N 9.97 min Cyclotron
16O(p, α)13N
H2O
H2O+ethanol
[13N]NO2/3
[13N]NH3
100% β+, 1200 keV
11C 20.4 min Cyclotron
14N(p,α)11C
N2(+O2)
N2(+H2)
[11C]CO2
[11C]CH4
99% β+, 960 keV
18F 109.8 min Cyclotron
20Ne(d,α)18F
18O(p,n)18F
Ne(+F2)
[18O]H2O
[18F]F2
[18F]F aq.
97% β+, 630 keV; 3% electron capture
68Ga 68 min Generator
(68Ge/68Ga)
68Ge, parent isotope [68Ga]GaCl3 90% β+, 1830 keV; 10% electron capture
64Cu 12.7 h Cyclotron
64Ni(p,n)64Cu
64Ni-enriched sample [64Cu]CuCl2 18% β+, 650 keV; 39% β, 579 keV; 43% electron capture
89Zr 78.4 h Cyclotron
89Y(p,n)89Zr
89Y-enriched sample [89Zr]Zr(C2O4)2 77% electron capture; 23% β+, 902 keV