Table 1.
Mean values of selected biochemical variables registered in the different conditions (normoxia, hypoxia 3000 m) at rest, after incremental test (max) and after 1 h recovery period (after 1 h).
| Variables | Normoxia (N) | Hypoxia 3000 m (H3) | Significance of Differences (* p < 0.05; ** p < 0.01) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| at Rest (1) |
Max (2) |
after 1 h (3) |
at Rest (4) |
Max (5) |
after 1 h (6) |
||||||||
| x ± SD | Me | x ± SD | Me | x ± SD | Me | x ± SD | Me | x ± SD | Me | x ± SD | Me | ||
|
ET-1 (pg/mL) |
2.5 ± 0.8 | 2.5 | 2.4 ± 1.7 | 2.3 | 2.0 ± 1.1 | 1.8 | 2.3 ± 0.8 | 2.5 | 2.3 ± 1.0 | 2.61 | 2.7 ± 1.2 | 2.5 | |
|
NO2− (pg/mL) |
28.7 ± 12.1 | 23.2 | 47.6 ± 21.2 | 38.8 | 30.2 ± 12.7 | 25.6 | 33.8 ± 16.3 | 39.1 | 52.3 ± 16.3 | 49.8 | 29.5 ± 9.3 | 26.3 |
N: X2 = 13.81; p = 0.001 1–2 *; 2–3 * H3: X2 = 16.9; p = 0.002 4–5 *; 5–6 * |
|
C (pg/mL) |
8.7 ± 4.1 | 7.1 | 11.5 ± 3.8 | 11.1 | 12.4 ± 1041 | 9.8 | 7.2 ± 2.7 | 6.7 | 8.2 ± 2.48 | 8.8 | 9.4 ± 5.9 | 7.2 |
N vs. H3: 2–5 * (U = 29.0; p = 0.041) |
|
NA (pg/L) |
338.9 ± 213.4 | 337.2 | 555.6 ± 25.6 | 575.6 | 406.8 ± 28.4 | 329.3 | 334.6 ± 153.2 | 238.7 | 1109.2 ± 1045.4 | 348.5 | 575.2 ± 359 | 435.2 | |
|
A (pg/L) |
53.9 ± 29.4 | 48.8 | 479 ± 358.1 | 369 | 112.5 ± 102.3 | 117.1 | 206.9 ± 70.7 | 228.5 | 1436.1 ± 622.9 | 1384.7 | 827.4 ± 263.7 | 742.7 |
N: X2 = 16.9; p = 0.002 1–2 *; 2–3 * H3: X2 = 18.2; p = 0.001 4–5 *; 4–6 * N vs. H3: 1–4 ** (U = 1.0; p = 0.001) 2–5 ** (U = 9.0; p = 0.001) 3–6 ** (U = 0.0; p = 0.001) |
|
DA (pg/L) |
7.6 ± 10.9 | 4.3 | 8.9 ± 5.8 | 7.8 | 5.6 ± 1.4 | 5.7 | 7.3 ± 2.5 | 6.7 | 12.5 ± 2.7 | 13.2 | 12.1 ± 5.5 | 13.7 |
N: X2 = 10.1; p = 0.006 2–3 * H3: X2 = 10.4; p = 0.005 4–5 *; 4–6 * N vs. H3: 2–5 ** (U = 17.0; p = 0.008) 3–6 ** (U = 16.0; p = 0.006) |
|
5-HT (pg/L) |
155.1 ± 104.2 | 135.4 | 212.6 ± 148.1 | 150.3 | 192.1 ± 90.1 | 190.7 | 136.5 ± 67.1 | 156.7 | 205.9 ± 124.3 | 150.4 | 156.4 ± 82.1 | 148.3 | |
x—arithmetic means; SD—standard deviations; Me—median; ET-1—endothelin-1; C—cortisol; NA—noradrenaline; A—adrenalin; DA—dopamine; 5-HT—serotonin; * p < 0.05; ** p < 0.001.