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The structure of EYA2 in the absence and presence of an inhibitor. (a) The structure of free EYA2 ED (PDB access code 4EGC). Mg2+ is present in the structure; (b) The structure of inhibitor bound EYA ED (PDB access code 5ZMA). No Mg2+ is present in the structure; (c) A cut-view of the inhibitor-bound EYA2 ED showing that the inhibitor highlighted in green binds deeply in a pocket.
