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TRPV2 over-expression enhanced CIS sensitivity. Untransfected and TRPV2+ cells were treated for 72 h with different concentrations of CIS, DOX (up to 100 μg/mL) and PAC (up to 4 μg/mL). Data shown are expressed as mean ± SD of three separate experiments. * p < 0.05 treated vs. vehicle, # p < 0.05 TRPV2+ vs. control.
