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Establishment of natural aging animal model. Wild‐type C57 mice were divided into young and old groups. (A) Photograph of mice. (B) Body weight (g). (C) Expression of GLB1, p53, p21, and p16 detected through western blotting; GAPDH: internal reference. (D) Relative protein expression levels of GLB1, p53, p21, and p16. N = 6; ** P < 0.01 and *** P < 0.001.
