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. 2020 Jun 28;11(4):1121–1140. doi: 10.1002/jcsm.12588

FIGURE 4.

FIGURE 4

Downstream mitogen‐activated protein kinase (MAPK) signalling upon eccentric contraction (ECC) in wild type (WT) and PolgA EDL. pSAPK/JNK, but not p44/42 MAPK ERK1/2 increased upon ECC both at 40 (A,B) and 46 weeks (D,E). (C,F) representative blots. Data represent mean ± SEM, n = 6–7/group, within genotypes: * P < 0.05, ** P < 0.001 ECC (squares/striped bars) vs. CTL (circles/solid bars) by paired Student's t‐test, between genotypes: (#)P < 0.10, #P < 0.05 by unpaired Student's t‐test ∆ECC‐CTL and basal values.