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. 2020 Jul 30;21(15):5422. doi: 10.3390/ijms21155422

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Rat behavior in the elevated zero maze (EZM) following exposure to the adulthood stress with or without preexposure to juvenile stress: J + A rats (n = 14) spent less time in the open quadrants of the EZM compared to all other groups (A). J + A rats showed lower activity levels in the open quadrants of the EZM compared to control (n = 14) and adult stress-exposed rats (n = 14) and a trend towards reduced activity compared to juv stress exposed rats (n = 14) (B). No significant reduction in total activity levels in the EZM was observed (C). ** Significant difference from control, p < 0.01; $ significant difference from juv stress, p < 0.05; # significant difference from adult stress, p < 0.05; and ~ border line significant difference from juv stress, p < 0.06.