Table 7.

Toxic effects of Capsicum.

Toxic Activities	Bioactive Compound/Type of Extract	Mechanism of Action of Toxicity	Ref.
Hemorrhage of the gastric fundus	Capsaicin 161.2 mg/kg (rats) and 118.8 mg/kg (mice).	Triggers painful irritation of the mucous membrane.	[204,205]
Myocardial infarction	40-year-old man admitted to emergency division with complains of chest discomfort and dyspnea after exposure to pepper gas.	Irritation of the mucous membrane.	[184]
Tenacious dermatitis	Capsaicin	Irritation of the skin.	[208]