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. 2020 Jul 22;21(15):5190. doi: 10.3390/ijms21155190

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of HC-3, Amb4269951, and Amb4269675 on [³H]choline uptake in MIA PaCa-2 cells (n = 3). Cells incubated with HC-3, Amb4269951, and Amb4269675 for 20 min and then 10 µM [³H]choline uptake measured for 20 min. Results calculated as 100% of findings in vehicle control. IC₅₀ values of HC-3, Amb4269951, and Amb4269675 for inhibition of [³H]choline uptake were 38.4, 2.4, and 6.0 µM, respectively.