DDR | DNA damage response |
Doxo | Doxorubicin |
Erk1,2 | Extracellular signal-regulated kinase 1, 2 |
γH2AX | S139 phosphorylated histone H2AX |
HGF | Hepatocyte growth factor |
JNJ | JNJ-38877606 |
PD | PD98059 |
RISK pathway | Reperfusion injury salvage kinase pathway |
ROS | Reactive oxygen species |
Stat3 | Signal transducer and activator of transcription 3 |
Timp1 | Tissue inhibitor of metalloproteinases-1 |