Table 3.
Antimicrobial activities of turgencin A and the synthesized StAMP-1–11 peptides.
| Antimicrobial Activity (MIC; µg/mL) 1 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Gram-Pos | Gram-Neg | Fungi | ||||||||
| Peptide | Bm | Bs | Cg | Ml | Sa | Ec | Pa | Ap | Ca | Rh |
| Turgencin A 2 | 0.5 | 1.5 | 1.5 | 8.0 | 23.3 | 3.0 | 5.9 | 92.6 | 46.3 | 23.2 |
| StAMP-1 | 250 | >250 | 250 | >250 | >250 | >250 | >250 | >250 | >250 | >250 |
| StAMP-2 | 3.9 | 125 | 31.3 | 250 | >250 | >250 | >250 | 62.5 | 125 | 62.5 |
| StAMP-3 | 3.9 | >250 | 15.6 | 250 | >250 | >250 | >250 | 62.5 | 125 | 62.5 |
| StAMP-4 | 3.9 | 125 | 3.9 | 125 | >250 | >250 | >250 | 62.5 | 62.5 | 31.3 |
| StAMP-5 | 1.0 | 15.6 | 2.0 | 15.6 | >250 | 31.3 | 250 | 31.3 | 31.3 | 15.6 |
| StAMP-6 | 1.0 | 3.9 | 3.9 | 62.5 | 250 | 62.5 | >250 | 62.5 | 62.5 | 31.3 |
| StAMP-7 | 1.0 | 3.9 | 2.0 | 31.3 | 125 | 31.3 | 250 | 15.6 | 31.3 | 15.6 |
| StAMP-8 | 3.9 | 7.8 | 7.8 | 15.6 | 125 | 62.5 | 125 | 7.8 | 15.6 | 15.6 |
| StAMP-9 | 1.0 | 3.9 | 2.0 | 3.9 | 7.8 | 7.8 | 31.3 | 31.3 | 31.3 | 15.6 |
| StAMP-10 | 3.9 | 7.8 | 7.8 | 15.6 | 62.5 | 15.6 | 31.3 | 62.5 | 62.5 | 15.6 |
| StAMP-11 | 7.8 | >250 | 31.3 | 62.5 | >250 | >250 | >250 | 250 | 125 | 31.3 |
| Indolicidin | 3.1 | 6.3 | 1.6 | 12.5 | 12.5 | 25.0 | >250 | 25.0 | 100 | 25.0 |
| Oxytetracycline | 0.6 | 10.0 | 0.2 | 1.3 | 0.04 | 1.3 | 2.5 | n.t 3 | n.t | n.t. |
| Triclosan | n.t | n.t | n.t | n.t | n.t | n.t | n.t | 3.1 | 3.1 | 1.6 |
1 Microbial strains: Bm—Bacillus megaterium, Bs—Bacillus subtilis, Cg—Corynebacterium glutamicum, Ml—Micrococcus luteus, Sa—Staphylococcus aureus, Ec—Escherichia coli, Pa—Pseudomonas aeruginosa, Ap—Aurobasidium pollulans, Ca—Candida albicans, Rh—Rhodotorula sp. 2 Antibacterial data for turgencin A against Bs, Cg, Sa, Ec and Pa are derived from Hansen et al. [24]. 3 nt: Not tested.