Table 1.
Study | Species | Sample | Increased Expression |
---|---|---|---|
Todd et al. [49] | Human | Peripheral blood | APOA1, complement C1r subcomponent, ICAM5, CC-motif chemokine 18, 14-3-3 SFN, sonic hedgehog protein, Oxidized low density lipoprotein. Receptor 1, MMP3, macrophage capping protein, HSP90β-1. |
Foster et al. [50] | Human | BALF | Eosinophil cationic protein, eosinophil lysophospholipase, MMP8, osteopontin, CC-motif chemokine 18 and collagens. |
Carleo et al. [51] | Human | BALF | Polymeric immunoglobulin receptors, α-1-B-glycoprotein, fibrinogen-γ, α-1-antitrypsin, complement C3, isocitrate, dehydrogenase, peroxiredoxin 1, ceruloplasmin, serotransferrin, SPA2 and hemopexin. |
Ohlmeier et al. [52] | Human | BALF | esRAGE |
Tian et al. [53] | Human | Lung | Collagen 1, cathepsin B, AGR-2, galectin-7, HSP90α, HSP90β |
Landi et al. [54] | Human | Lung | Alpha-1-antitripsin, SEPRINA3, GSTP1, 14-3-3, HSF-1, NF-AT4, C-Myc |
Korfei et al. [55] | Human | Lung | HSP90α, HSP90β, HSP60 |
Schiller et al. [56] | mice | Lung | Emylin-2, Collagen-XXVIII, Wnt1 |
Summarized data from different proteomic studies on IPF. APOA1: Apolipoprotein A-1, ICAM-5: intracellular adhesion molecule 5; SFN 14-3-3 protein Sigma; MMP3: Matrix MetalloProteinase 3; HSP90β-1: Heat Shock Protein 90β-1; MMP8: Matrix MetalloProteinase 8; SPA2: Surfactant Associated Protein A2; esRAGE: endogenous soluble form of Receptor for Advanced Glycation End-products; AGR-2: Anterior Gradient Protein 2; HSP90α: Heat Shock Protein α; SEPRINA3: alpha-1-antychymotripsin; GSTP1: Glutathione S Transferase P1; HSF-1: Heat Shock Factor 1; NF-AT4: Nuclear Factor of Activated T cell.