Table 1.
Baseline, treatment, and changes in the clinical and metabolic characteristics of participants in the ethanol-free control (CTL) and the group that consumed 35 g ethanol daily for eight weeks (EtOH).
| CTL Δ W0 vs. W8 |
EtOH Δ W0 vs. W8 |
Δ CTL vs. Δ EtOH | Effect Size Δ CTL vs. Δ EtOH |
p-Value Δ CTL vs. Δ EtOH |
|
|---|---|---|---|---|---|
| BMI (kg/m2) | −2.2 ± 0.4 a | −2.0 ± 0.3 a | −0.2 ± 0.5 | −0.2 | 0.76 |
| Body weight (kg) | −6.6 ± 1.2 a | −5.4 ± 0.8 a | −1.2 ± 1.4 | −0.6 | 0.43 |
| SAT (kg) | −1.1 ± 0.3 a | −1.2 ± 0.2 a | 0.05 ± 0.3 | 0.1 | 0.87 |
| VAT (kg) | −0.2 ± 0.1 | −0.1 ± 0.1 | −0.2 ± 0.1 | −0.9 | 0.23 |
| Triglycerides (mg/dL) | −26.3 ± 20.3 | 16.6 ± 13.3 | −42.9 ± 24.3 | −1.2 | 0.11 |
| FFA (mmol/L) | 0.1 ± 0.1 | 0.2 ± 0.1 a | −0.1 ± 0.1 | −0.3 | 0.62 |
| Glycerol (mmol/L) | −0.01 ± 0.02 | 0.02 ± 0.02 | −0.03 ± 0.03 | −0.8 | 0.33 |
| Cholesterol (mg/dL) | −26.7 ± 9.9 a | -5.6 ± 6.5 | −21.1 ± 11.8 | −1.2 | 0.11 |
| HDL (mg/dL) | −5.7 ± 3.7 | -4.3 ± 2.4 | −1.4 ± 4.4 | −0.2 | 0.76 |
| LDL (mg/dL) | −15.7 ± 8.3 | -4.6 ± 5.4 | −11.1 ± 9.9 | −0.8 | 0.29 |
| Mean Arterial Pressure (mmHg) | −8.3 ± 2.3 a | −0.4 ± 1.5 | −8.0 ± 2.8 | −2.0 | 0.02 |
| Glucose (mg/dL) | −3.0 ± 4.5 | 3.3 ± 3.0 | −6.3 ± 5.4 | −0.8 | 0.28 |
| Insulin (mU/L) | −6.8 ± 3.3 | −5.2 ± 2.1 a | −1.6 ± 3.9 | −0.3 | 0.70 |
| HOMA-IR | −1.7 ± 0.85 | −1.1 ± 0.6 | −0.6 ± 1.0 | −0.4 | 0.58 |
| Uric Acid (mg/dL) | −0.5 ± 0.3 | 0.3 ± 0.2 | −0.8 ± 0.4 | −1.4 | 0.07 |
Values presented as mean ± SEM; a p < 0.05 for within-group change in measured outcome