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. 2020 Jul 22;21(15):5181. doi: 10.3390/ijms21155181

Figure 3.

Figure 3

Co-stimulatory immune checkpoint OX40 expression on circulating Treg of human papillomaviruses (HPV)+ tumor patients (n = 7) was significantly increased compared to HPV− patients (n = 16). Mann–Whitney test was used to determine significance, with p = 0.0015. The expression of immune checkpoints on peripheral blood lymphocytes was measured by flow cytometry. p-value < 0.01 was considered to be significant with (**).