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. 2020 Aug 7;6(8):e04589. doi: 10.1016/j.heliyon.2020.e04589

Table 11.

Model fitting for release profile.

Nano particles Coefficient of determination (R2)
Best fit model
First order Zero order Higuchi Hixon-Crowel cube root
Surface modified PLGA 75:25 0.0275 0.9369 0.9654 0.9583 Higuchi
Surface modified PLGA 50:50 0.9578 0.9262 0.9979 0.9762 Higuchi