Table 3.

3³ Box-Behnken statistical design layout, experimental runs and their combinations.

Runs	Batch no.	Factor 1 A	Factor 2 B	Factor 3 C
1	B1	0	0	0
2	B2	-1	0	+1
3	B3	0	+1	+1
4	B4	-1	0	-1
5	B5	+1	-1	0
6	B6	+1	+1	0
7	B7	0	0	0
8	B8	+1	0	-1
9	B9	0	-1	-1
10	B10	0	+1	-1
11	B11	0	0	0
12	B12	0	-1	+1
13	B13	-1	+1	0
14	B14	+1	0	+1
15	B15	-1	-1	0