Table 5.

Experimental runs.

Runs	Batch No.	Factor 1 A: PLGA (mg)	Factor 2 B: P80 (mg)	Factor 3 C: cycles (numbers)	Response1 Particle size (nm)	Response 2 PDI	Response 3 E.E. (%)
1	B1	200	450	7	182	0.323	85
2	B2	100	450	8	163	0.286	91
3	B3	200	600	8	179	0.359	86
4	B4	100	450	6	172	0.310	82
5	B5	300	300	7	189	0.388	91
6	B6	300	600	7	186	0.364	94
7	B7	200	450	7	182	0.323	85
8	B8	300	450	6	192	0.387	90
9	B9	200	300	6	185	0.289	87
10	B10	200	600	6	186	0.321	88
11	B11	200	450	7	185	0.368	86
12	B12	200	300	8	173	0.283	88
13	B13	100	600	7	169	0.267	82
14	B14	300	450	8	186	0.354	93
15	B15	100	300	7	166	0.288	81