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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Mol Carcinog. 2020 Jan 2;59(2):237–245. doi: 10.1002/mc.23151

FIGURE 2.

FIGURE 2.

CVB housing increases host but reduces donor memory T cell proportions in the spleen following allogeneic LN cell infusion. Lymph node (LN) cells from SPF B6-CD45.1 donors were infused into CByB6F1 recipients in both CVB and SPF facilities at 28 × 106 cells/mouse. Animals were euthanized 17 days later and spleen cells were extracted and analyzed. A, Proportions of CD44+ memory CD4 and CD8 T cells in CVB-CON and SPF-CON control mice (CD45.1−) shown as representative dot plots. B, Proportions of CD44+ memory CD4 and CD8 T cells in CVB-CON and SPF-CON control mice shown as means with standard errors. C, Proportions of donor-type (CD45.1+) or host-type (CD45.1−) CD4+CD44+ and CD8+CD44+ memory T cells in CVB-BMF and SPF-BMF mice shown as representative dot plots. D, Proportions of donor-type (CD45.1+) CD4+CD44+ and CD8+CD44+ memory T cells in CVB-BMF and SPF-BMF mice shown as means with standard errors. *, P<.05.