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. Author manuscript; available in PMC: 2020 Aug 18.
Published in final edited form as: Leukemia. 2018 Jul 26;33(1):217–229. doi: 10.1038/s41375-018-0204-z

Table 1.

Clinical and laboratory characteristics of MDS patients

No. % BM blasts 2016 WHO classification Karyotype IPSS risk IEX-1 mRNA % CD71+ reticulocytes % Mito reticulocytes
Other MDS 1 <5 MDS-MLD Del(11q23), + 8 Int-1 0.7 0.29 13.7
2 <5 MDS-MLD Add(1)(p23) Int-1 1.5 4.42 4.5
3 <5 MDS-MLD Normal Int-1 0.8 2.33 34.3
4 15 t-MDS −7 High 0.6 0.33 22.8
6 <5 t-MDS Normal Int-1 0.7 2.27 24.3
9 6 CMML-1 (low WBC dysplastic subtype) Normal Int-1 3.0 1.13 33
10 6 MDS-EB1 (rings 30%) Complex Int-2 2.6 1.52 39.2
11 <5 MDS/MPN-RS-T Normal Low 4.5 0.40 24.4
12 <5 MDS-MLD Normal Int-1 1.4 2.13 34
13 7 MDS-EB1 Complex Int-2 1.0 0.72 2.7
14 <5 MDS-SLD-RS Normal Low 2.5 0.68 32.4
15 8 MDS-EB1 Complex Int-2 0.7 0.96 37.4
16 9 MDS-EB1 Normal Int-1 1.8 3.04 29.6
18 <5 MDS-MLD Del(20) (q12q13) Int-1 0.9 0.50 43.8
19 <5 t-MDS Der(1;7), + 1 Int-1 0.6 0.30 44.7
20 <5 MDS-MLD-RS Normal Low 1.0 4.49 1.7
21 <5 MDS-SLD-RS Normal Low 0.8 0.10 4.7
22 8 t-MDS +13 Int-2 0.8 0.01 17.1
Low IEX-1 5 18 MDS-EB2 Del(5)(q13q33) Int-2 0.3 1.41 69.0
7 14 MDS-EB2 Del(9)(q) High 0.2 1.84 70.8
8 <5 t-MDS Der(1;7), +1 Int-1 0.3 1.02 73.4
17 9 MDS-EB1 Normal Int-1 0.3 1.03 67.9
23 <5 MDS-MLD Del(20) (q12q13) Low 0.3 1.68 62.8
Average value of healthy donors (mean ± SD): 1.0 ± 0.4 0.06 ± 0.04 5.4 ± 3.2