Table 1.
No. | % BM blasts | 2016 WHO classification | Karyotype | IPSS risk | IEX-1 mRNA | % CD71+ reticulocytes | % Mito− reticulocytes | |
---|---|---|---|---|---|---|---|---|
Other MDS | 1 | <5 | MDS-MLD | Del(11q23), + 8 | Int-1 | 0.7 | 0.29 | 13.7 |
2 | <5 | MDS-MLD | Add(1)(p23) | Int-1 | 1.5 | 4.42 | 4.5 | |
3 | <5 | MDS-MLD | Normal | Int-1 | 0.8 | 2.33 | 34.3 | |
4 | 15 | t-MDS | −7 | High | 0.6 | 0.33 | 22.8 | |
6 | <5 | t-MDS | Normal | Int-1 | 0.7 | 2.27 | 24.3 | |
9 | 6 | CMML-1 (low WBC dysplastic subtype) | Normal | Int-1 | 3.0 | 1.13 | 33 | |
10 | 6 | MDS-EB1 (rings 30%) | Complex | Int-2 | 2.6 | 1.52 | 39.2 | |
11 | <5 | MDS/MPN-RS-T | Normal | Low | 4.5 | 0.40 | 24.4 | |
12 | <5 | MDS-MLD | Normal | Int-1 | 1.4 | 2.13 | 34 | |
13 | 7 | MDS-EB1 | Complex | Int-2 | 1.0 | 0.72 | 2.7 | |
14 | <5 | MDS-SLD-RS | Normal | Low | 2.5 | 0.68 | 32.4 | |
15 | 8 | MDS-EB1 | Complex | Int-2 | 0.7 | 0.96 | 37.4 | |
16 | 9 | MDS-EB1 | Normal | Int-1 | 1.8 | 3.04 | 29.6 | |
18 | <5 | MDS-MLD | Del(20) (q12q13) | Int-1 | 0.9 | 0.50 | 43.8 | |
19 | <5 | t-MDS | Der(1;7), + 1 | Int-1 | 0.6 | 0.30 | 44.7 | |
20 | <5 | MDS-MLD-RS | Normal | Low | 1.0 | 4.49 | 1.7 | |
21 | <5 | MDS-SLD-RS | Normal | Low | 0.8 | 0.10 | 4.7 | |
22 | 8 | t-MDS | +13 | Int-2 | 0.8 | 0.01 | 17.1 | |
Low IEX-1 | 5 | 18 | MDS-EB2 | Del(5)(q13q33) | Int-2 | 0.3 | 1.41 | 69.0 |
7 | 14 | MDS-EB2 | Del(9)(q) | High | 0.2 | 1.84 | 70.8 | |
8 | <5 | t-MDS | Der(1;7), +1 | Int-1 | 0.3 | 1.02 | 73.4 | |
17 | 9 | MDS-EB1 | Normal | Int-1 | 0.3 | 1.03 | 67.9 | |
23 | <5 | MDS-MLD | Del(20) (q12q13) | Low | 0.3 | 1.68 | 62.8 | |
Average value of healthy donors (mean ± SD): | 1.0 ± 0.4 | 0.06 ± 0.04 | 5.4 ± 3.2 |