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. Author manuscript; available in PMC: 2020 Aug 18.
Published in final edited form as: Nat Nanotechnol. 2018 Oct 29;13(11):1078–1086. doi: 10.1038/s41565-018-0274-0

Fig. 1 |. Schematic and particle fabrication.

Fig. 1 |

a, Schematic of spiky particles applied to activate immune cells and amplify immune responses in vivo. b,c, SEM (b) and TEM (c) images of spiky particles. d,e, SEM images of rough particles (d) and the sonicated-off nanospikes (nanorods) (e).