Figure 5.

LM‐031 decreases Aβ and Tau immunoreactivity in STZ‐treated 3 × Tg‐AD mice. Mice in – STZ, STZ, and STZ/LM‐031 groups received vehicle, STZ, and STZ + LM‐031, respectively, during the course of the experiment. Representative IHC images for Aβ (a) and Tau (b), and intensity and area quantification in the hippocampus and cortex of mice. p values, STZ versus –STZ mice or STZ/LM‐031 versus STZ mice. ^#: p < .05, ^## and **: p < .01, and ^### and ***: p < .001. (one‐way ANOVA with a post hoc Tukey test)