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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Depress Anxiety. 2020 Jan;37(1):63–72. doi: 10.1002/da.22911

Table 2.

Estimated (Least Square) Means (LSM) of PTSD symptom severity, trauma-related guilt severity, and functional impairment at baseline and end-of-treatment (week 24) in post-9/11 combat veterans with and without comorbid complicated grief (CG).

no CG CG

Outcome week LSM 95% CL LSM 95% CL Pair-wise p<.05 SDpooled d interaction contrast p

CAPS total scores 0 76.4 [73.0, 79.8] 83.0 [37.2, 47.7] 0.005 14.0 0.47 0.079
24 42.4 [78.1, 87.9] 57.2 [48.4, 66.0] 0.003 25.8 0.57
TRGI global guilt 0 1.44 [1.17, 1.71] 2.34 [1.94, 2.74] <.001 1.16 0.78 0.632
24 0.84 [0.58, 1.10] 1.64 [1.24, 2.04] <.001 1.07 0.75
TRGI distress 0 2.39 [2.21, 2.57] 2.92 [1.63, 2.05] <.001 0.80 0.67 0.495
24 1.84 [2.65, 3.19] 2.24 [1.90, 2.58] 0.025 0.94 0.43
TRGI guilt cog. 0 0.78 [0.61, 0.94] 1.22 [0.98, 1.46] <.001 0.68 0.65 0.566
24 0.59 [0.42, 0.76] 0.96 [0.70, 1.22] 0.004 0.70 0.53
IFI total scores 0 40.3 [37.3, 43.4] 45.3 [40.7, 49.9] 0.033 14.3 0.35 0.417
24 34.9 [31.5, 38.2] 37.5 [32.2, 42.8] 0.324 15.0 0.18

Note: Estimated marginal means were adjusted for treatment type, site, gender, and (for all models except CAPS total scores) CAPS baseline scores in maximum-likelihood mixed models. The effect size d is based on LSM differences divided by the raw pooled standard deviation (SDpooled). The interaction contrast tests whether the no CG vs. CG group difference observed at baseline significantly differs from that at end of treatment (week 24).